A series of informational 1 page documents outlining various aspects of Cannabis medicines
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Infographics
DIPG, Elyse Defying the odds.
Article by Casey Johnson, Mother to Elyse.Our daughter Elyse who is now four years old, was diagnosed with a rare and aggressive brain tumour called diffuse intrinsic pontine glioma (DIPG) on April 9th 2016 just over 2 years old.This tumor has a very low survival rate with less than 1% of its victims beating the odds. It predominantly affects children and most pass away within 3-9 mont...
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Anandamide
Anandamide was discovered in 1992 by a team working for Raphael Mechaloum. Its name comes from ananda, the Sanskrit word for "bliss", and its is also known in scientific terms as N-arachidonoylethanolamine or AEA, and is a naturally occurring cannabinoid within the human body. Anandamide closely resembles tetrahydrocannabinol, or THC. Anandamide has an effect on both the CB₁ and CB₂ receptors; wit...
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Taming THC: potential cannabis synergy and phytocannabinoid-terpenoid entourage effects
Author: Ethan B Russo
Abstract
Tetrahydrocannabinol (THC) has been the primary focus of cannabis research since 1964, when Raphael Mechoulam isolated and synthesized it. More recently, the synergistic contributions of cannabidiol to cannabis pharmacology and analgesia have been scientifically demonstrated. Other phytocannabinoids, including tetrahydrocannabivarin, cannabigerol and cannabichromen...
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Taming THC: potential cannabis synergy and phytocannabinoid-terpenoid entourage effects.
Author Russo EB
AbstractTetrahydrocannabinol (THC) has been the primary focus of cannabis research since 1964, when Raphael Mechoulam isolated and synthesized it. More recently, the synergistic contributions of cannabidiol to cannabis pharmacology and analgesia have been scientifically demonstrated. Other phytocannabinoids, including tetrahydrocannabivarin, cannabigerol and cannabichromene,...
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Cannabis Or Pain Killers? A Chicago Doctor Makes A Compelling Argument
I have been a practicing physician in the Chicago land area for more than 30 years with a specialty in pain medicine. A recent report from the Centers for Disease Control and Prevention draws attention to the fact that Illinois must allow patients the opportunity to choose cannabis over highly addictive and sometimes deadly prescription drugs.Opioids and narcotics remain the primary drugs for ...
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Efficacy and adverse effects of medical marijuana for chronic noncancer pain
Authors: Deshpande A, Mailis-Gagnon A, Zoheiry N, Lakha SF.
AbstractOBJECTIVE:
To determine if medical marijuana provides pain relief for patients with chronic noncancer pain (CNCP) and to determine the therapeutic dose, adverse effects, and specific indications.
DATA SOURCES:
In April 2014, MEDLINE and EMBASE searches were conducted using the terms chronic noncancer pain, smoked marijuana...
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Controlled release tablet formulation containing natural Δ9-tetrahydrocannabinol.
Authors: Punyamurthula NS, Hingorani T, Adelli G, Gul W, ElSohly MA, Repka MA, Majumdar S
AbstractCannabinoids are increasingly being used in the treatment of chemotherapy-induced nausea and vomiting (CINV) because of their action on thecannabinoid receptors, CB1 and CB2. The currently marketed capsule formulations (sesame oil based and crystalline powder) are required to be administered freque...
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Our Story – DIPG Brain Tumor
My beautiful one and only Granddaughter was born on the first day of spring 2010 and I was thrilled, scared, overjoyed, nervous, and oh so very much in love from the first time I set eyes on her. My daughter just 19 years old, back at home with me after having left her partner. It is now 2015 and my wee granddaughter is 5 years old and has brain cancer.This year has been a total trai...
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Advances in the management of MS symptoms: real-life evidence.
Author: Trojano M.
AbstractOnce the efficacy and tolerability of a new intervention have been demonstrated in clinical trials under ideal experimental conditions, observational studies within approved label conditions are performed to determine its effectiveness in real-world use and expand the safety/tolerability data. Several large observational studies have been conducted of Sativex(®) (THC:...
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