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cannabinoid

Medicinal Cannabis—Potential Drug Interactions

Original article found hereMuhammad A. Alsherbiny 1,2,*  and Chun Guang Li 1,* 1 NICM Health Research Institute, Western Sydney University, Westmead, NSW 2145, Australia2 Department of Pharmacognosy, Faculty of Pharmacy, Cairo University, Cairo 11562, EgyptAbstract The endocannabinoids system (ECS) has garnered considerable interest as a potential therapeutic target in var...
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Marijuana-derived Δ-9-tetrahydrocannabinol suppresses Th1/Th17 cell-mediated delayed-type hypersensitivity through microRNA regulation.

Abstract∆9-Tetrahydrocannabinol (THC) is one of the major bioactive cannabinoids derived from the Cannabis sativa plant and is known for its anti-inflammatory properties. Delayed-type hypersensitivity (DTH) is driven by proinflammatory T helper cells including the classic inflammatory Th1 lineage as well as the more recently discovered Th17 lineage. In the current study, we investigated whet...
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Peripherally Restricted Cannabinoids for the Treatment of Pain.

Authors: Romero-Sandoval EA, Asbill S, Paige CA, Byrd-Glover K. AbstractThe use of cannabinoids for the treatment of chronic diseases has increased in the United States, with 23 states having legalized the use of marijuana. Although currently available cannabinoid compounds have shown effectiveness in relieving symptoms associated with numerous diseases, the use of cannabis or cannabinoids ...
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Cannabinoids in the management of chronic pain: a front line clinical perspective.

Author: Mary E. LynchAbstract Chronic pain is an escalating public health problem. Currently available treatments are inadequate to control chronic pain conditions, and there is a critical need for novel treatments. Over a half century of elegant preclinical research has identified the presence of a sophisticated endocannabinoid system that is part of our natural pain and immune defense netwo...
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