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Anaemia

Cannabinoid Receptor-Specific Mechanisms To Ameliorate Pain In Sickle Cell Anemia Via Inhibition Of Mast Cell Activation And Neurogenic Inflammation

Authors: Lucile Vincent, Derek Vang, Julia Nguyen, Barbara Benson, Jianxun Lei, Kalpna Gupta. Abstract Sickle cell anaemia is a manifestation of a single point mutation in haemoglobin, but inflammation and pain are the insignia of this disease which can start in infancy and continue throughout life. Earlier studies showed that mast cell activation contributes to neurogenic inflammation and pain in...
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